Liver and nervous system


1. Institute of Experimental Medicine, Russian Academy of Medical Sciences
Type: Review
PubMed Id: 15179820
Year: 2004 vol: 50  issue:2  pages: 136-149
Abstract: This review considers the liver adrenergic and cholinergic innervation in connection with its trophic function. The attempt was made to analyse mechanisms of nervous regulation of liver metabolism and to estimate the role of co-transmitters in metabolic functions of the peptidergic fibers. Liver and portal vein afferent sensors for amino acids, glucose, insulin, glucagon, leptin and osmosensors were described. These sensors detect the liver metabolic signals and transmit them by vagal hepatic afferents to the network of hypothalamic and cortical structures.
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Reference: Parfenova N.S., Liver and nervous system, Biomeditsinskaya khimiya, 2004, vol: 50(2), 136-149.