Abstract: The relationship between the increase in maternal serum concentration of pregnancy-specific beta 1-glycoprotein (SP1) and levels of components of hemostasis system was investigated. The concentrations of SP1 were measured in the blood sera of 234 pregnant women with recurrent spontaneous abortions, in 115 somatically healthy pregnant women and 75 donors. A direct correlation between serum SP1 and levels of components of hemostasis system was shown. Results suggest that disturbances in hemostasis system influence synthesis of some placental proteins, including SP1.
Reference: Bogdanovich R.N., Chikalovets I.V., Berestovay T.A., System of hemostasis and pregnancy-specific beta 1-glycoprotein in treatened abortion, Biomeditsinskaya khimiya, 2004, vol: