Circulating nucleic acids in blood of patients with malignant tumors of gastrointestinal tract

   


1. Institute of chemical Biology and Fundamental Medicine SB of RAS
2. Novosibirsk Oncological Dispensary
Type: Experimental/clinical study
PubMed Id: 16104395
Year: 2005 vol: 51  issue:3  pages: 321-328
Abstract: Concentrations of extracellular deoxy- and ribonucleic acids in blood plasma and cell-surface-bound of blood cells were investigated in healthy donors and patients with malignant gastrointestinal tumor. Our results indicate that high concentration of extracellular DNA in blood plasma along with decreased level of extracellular RNA on the surface of blood cells correlate with development of gastrointestinal cancer. Ratio of nucleic acids in plasma to total amount of nucleic acids circulated in blood is a characteristic parameter distinguishing cancer patients healthy persons.
Download PDF:
Reference: Tamkovich S.N., Bryzgunova O.E., Rykova E.Yu., Kolesnikova E.V., Shelestuk P.I., Laktionov P.P., Vlassov V.V., Circulating nucleic acids in blood of patients with malignant tumors of gastrointestinal tract, Biomeditsinskaya khimiya, 2005, vol: 51(3), 321-328.
Bibliography
 2016(Vol:62)
 2015(Vol:61)
 2014(Vol:60)
 2013(Vol:59)
 2012(Vol:58)
 2011(Vol:57)
 2010(Vol:56)
 2009(Vol:55)
 2008(Vol:54)
 2007(Vol:53)
 2006(Vol:52)
 2005(Vol:51)
 2004(Vol:50)
 2003(Vol:49)