Role of membrane deformations in regulation of functions of cells

   


1. Tyumen State Medical Academy
2. Research Inst. For Addiction, Ministry for Health care
Type: Review
UDK:       PubMed Id: 16342663
Year: 2005 vol: 51  issue:5  pages: 473-480
Abstract: There is evidence that cells respond not only to biologically active substances, but also to external mechanical effects. This is especially important for cellular elements of vascular walls and blood. Mechanical treatment cause so-called stretch-deformation of plasma membranes and forces generated by shift of plasma layers induce shear stress. Good experimental evidence exists that mechanical effects influence functional activity of vascular wall and blood cells.
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Reference: Glushkov V.S., Storozhok S.A., Panchenko L.F., Silina E.G., Role of membrane deformations in regulation of functions of cells, Biomeditsinskaya khimiya, 2005, vol: 51(5), 473-480.
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