peculiarities of free radical antioxidant statute in patients with systemic lupus erythematosus and rheumatoid arthritis

   


1. Smolenskaya State Medical Academy
2. Institute of Rheumatology of RAMS
Type: Experimental/clinical study
UDK:       PubMed Id: 16342671
Year: 2005 vol: 51  issue:5  pages: 536-541
Abstract: The stade of lipid peroxidation and antioxidant defense was investigated in sera of 66 patients with rheumatoid arthritis (RA), 50 patients with systemic lupus erythematosus (SLE) and in 235 healthy donors using the method of chemiluminescence and EPR-spectroscopy. The results indicate involvement of free radical oxidation in pathogenesis of RA and SLE. Peroxide and antioxidant imbalance was more pronounced in RA than in SLE.
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Reference: Podoprigorova V.G., Bobilev A.A., Ivanova S.M., Speransky L.I., peculiarities of free radical antioxidant statute in patients with systemic lupus erythematosus and rheumatoid arthritis, Biomeditsinskaya khimiya, 2005, vol: 51(5), 536-541.
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