The influence of the 1-(2`-hydroxiethyl)-2-methyl-5-nitroimidazole on the state of erythrocyte membranes and their models

   


1. Saratov State University, Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences
2. Saratov State University
Type: Experimental/clinical study
UDK:       PubMed Id: 16521827
Year: 2005 vol: 51  issue:6  pages: 649-655
Abstract: Metronidazolum decreased diffusion mobility of membrane surface water. It is possible, that Wuk`s effect represents the molecular mechanism underlying this phenomenon. We suppose, that protective action of the derivatives of the nitroimidazole on cell lysis is related to changes of the diffusion mobility of the surface water
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Reference: Kuznetsov P.E., Popyhova E.B., Rogacheva S.M., Evlakov K.I., The influence of the 1-(2`-hydroxiethyl)-2-methyl-5-nitroimidazole on the state of erythrocyte membranes and their models, Biomeditsinskaya khimiya, 2005, vol: 51(6), 649-655.
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