The ability of bacterial DNA methyltransferases to use methylcobalamine as a cofactor in DNA methylation reactions

   


1. Laboratory of Genetics, Institute of Botany
Type: Experimental/clinical study
UDK: 547.963+577.157      PubMed Id: 17639716
Year: 2007 vol: 53  issue:2  pages: 159-163
Abstract: The ability of bacterial DNA methyltransferases Alu I, Cfr I, Cfr 6, Cfr 10, Eco RI, Eco RII, Msp I, Mva I, Pvu I, Pvu II, and Sau 3A to use methyl-cobalamine and methyl-methionine as cofactors of DNA methylation in vitro. These bacterial DNA methyl transferase used methyl-cobalamine, but not methyl-methionine for DNA methylation.
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Reference: Lebionka A.Yu., Melvidas V.I., The ability of bacterial DNA methyltransferases to use methylcobalamine as a cofactor in DNA methylation reactions, Biomeditsinskaya khimiya, 2007, vol: 53(2), 159-163.
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