To the problem of proteolytic enzyme evolution


1. Institute of Biology, Karelian Research Centre of RAS
Type: Review
UDK: 577.152.34:599.3      PubMed Id: 18421911
Year: 2008 vol: 54  issue:1  pages: 42-57
Abstract: Own and literature data on putative evolution of proteolytic enzymes have been reviewed. Modern principles of peptidase classification based on evaluation of homology of more than 66 thousand gene sequences and similarity of general structural organization of almost 2.5 thousands of known enzymes are considered. The review highlights not only evolutionary interrelationships inside related peptidase families, their possible evolutionary background, but also evolutionary determined differences in certain proteolytic pathway in organisms belonging to different taxons.
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Reference: Nemova N.N., Bondareva L.A., To the problem of proteolytic enzyme evolution, Biomeditsinskaya khimiya, 2008, vol: 54(1), 42-57.
This paper is also available as the English translation:10.1134/S1990750808020017