Molecular characteristics of testosterone binding globulin and analysis of their regulation

   


1. Institute of Radiobiology, Belarus Nat. Acad. Sci
2. International Sakharov Environmental University
Type: Experimental/clinical study
UDK: 612.12.018:577.175.62:].08      PubMed Id: 18712090
Year: 2008 vol: 54  issue:3  pages: 349-360
Abstract: Molecular characteristics of testosterone binding globulin (TeBG) were investigated in microaliquots of human serum samples using 3H-5-α-dihydrotestosterone radioligand assays. Under experimental conditions used TeBG demonstrated high conformational plasticity and ability to adopt three conformational states (olygo-, di-, and monomer) with different functional activities. Using a lipidspolyene complex from basidiomycete Laetiporus sulphureus we demonstrate a novel effective pharmacological correction of the TeBG characteristics.
Download PDF:
Reference: Popoff E.H., Kapich A.N., Molecular characteristics of testosterone binding globulin and analysis of their regulation, Biomeditsinskaya khimiya, 2008, vol: 54(3), 349-360.
Bibliography
 2016(Vol:62)
 2015(Vol:61)
 2014(Vol:60)
 2013(Vol:59)
 2012(Vol:58)
 2011(Vol:57)
 2010(Vol:56)
 2009(Vol:55)
 2008(Vol:54)
 2007(Vol:53)
 2006(Vol:52)
 2005(Vol:51)
 2004(Vol:50)
 2003(Vol:49)