The perspectives of hepatic failure treatment by stem cells


1. Institute of Transplantology and Artificial Organs, Rosmedtechnology
Type: Review
UDK: 616.1.9-055.5      PubMed Id: 18988455
Year: 2008 vol: 54  issue:4  pages: 376-391
Abstract: The insufficiency of liver functions remains one of the major causes of death. The liver transplantation is the most effective method for treating severe liver diseases. The shortage of donor organs and high risk of graft rejection are the main problems for liver transplantation. Stem cells and isolated hepatocytes are alternative means for repopulating the liver after various injuries instead of liver transplantation. This review analyses the experimental and clinical advantage and perspectives on the stem cells use in clinical trials for treating hepatic failure.
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Reference: Dolgikh M.S., The perspectives of hepatic failure treatment by stem cells, Biomeditsinskaya khimiya, 2008, vol: 54(4), 376-391.
This paper is also available as the English translation:10.1134/S1990750808030074