Abstract: The review is focused on the modern methods of radioimmune diagnostics of high-grade gliomas with monoclonal antibodies and other approaches of radioimmunolocalisation with pretargeted bispecific antibodies. High-grade tumor-related proteins were analysed as potential targets for radiolabeled antibodies. Recent experimental and clinical data and the most promising immunochemical approaches for diagnostic and targeted therapy of gliomas with tumor-specific antibodies are discussed.
Reference: Baklaushev V.P., Pavlov K.A., Chekhonin V.P., Monoclonal antibodies in diagnostics of high-grade gliomas, Biomeditsinskaya khimiya, 2009, vol:
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