Monoclonal antibodies in diagnostics of high-grade gliomas


1. Laboratory of Immunochemistry Serbsky National Centre for Social and Forensic Psychiatry
Type: Review
UDK: 616.097;576.8.077      PubMed Id: 19507338
Year: 2009 vol: 55  issue:2  pages: 140-154
Abstract: The review is focused on the modern methods of radioimmune diagnostics of high-grade gliomas with monoclonal antibodies and other approaches of radioimmunolocalisation with pretargeted bispecific antibodies. High-grade tumor-related proteins were analysed as potential targets for radiolabeled antibodies. Recent experimental and clinical data and the most promising immunochemical approaches for diagnostic and targeted therapy of gliomas with tumor-specific antibodies are discussed.
Download PDF:
Reference: Baklaushev V.P., Pavlov K.A., Chekhonin V.P., Monoclonal antibodies in diagnostics of high-grade gliomas, Biomeditsinskaya khimiya, 2009, vol: 55(2), 140-154.
This paper is also available as the English translation:10.1134/S1990750809020012