Fatty acid complex "bien" incorporation into liposomes multilayered


1. The Institute of Biophysics and Cell Engineering, National Academy of Sciences of Belarus
Type: Experimental/clinical study
UDK: 577. 352. 24: 615. 451.234.012      PubMed Id: 19507341
Year: 2009 vol: 55  issue:2  pages: 177-184
Abstract: The conditions of fatty acid complex "bien" incorporation into multilayered liposomes prepared by mechanical dispersion techniques (vortexing) have been investigated. Drug incorporation depends on the lipid composition used to prepare the vesicles, overall lipid and "bien" concentrations and the presence of an antioxidant. Vortexing and incubation regimes for the homogeneous liposomal suspension were determined. The effects of contents of DL-α-tocopherol and cholesterol on lipid peroxidation were evaluated.
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Reference: Bushmakina I.M., Drozdova N.I., Martynova M.A., Fatty acid complex "bien" incorporation into liposomes multilayered, Biomeditsinskaya khimiya, 2009, vol: 55(2), 177-184.