Metabolic fingerprinting of blood plasma for patients with prostate cancer

   


1. Institute of Biomedical Chemistry RAMS
Type: Experimental/clinical study
UDK: 543.51.061:543.54.45:543.8      PubMed Id: 19663000
Year: 2009 vol: 55  issue:3  pages: 247-254
Abstract: Application of blood plasma metabolites fingerprinting for the diagnostic of the 2nd stage of prostate cancer has been investigated. The diagnostic sensitivity (95%), specificity (96,7%) and accuracy (95,7%) of the metabolic fingerprinting were much higher then those for PSA test (35%, 83,3% and 51,7%, respectively) for the same patients. Area under the ROC-curve (0,994) suggests that the proposed approach is effective and can be used for clinical applications.
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Reference: Lokhov P.G., Dashtiev M.I., Bondartsсov L.V., Lisitsa А.V., Moshkovskii S.A., Archakov A.I., Metabolic fingerprinting of blood plasma for patients with prostate cancer, Biomeditsinskaya khimiya, 2009, vol: 55(3), 247-254.
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