Citrate influence on oxidative status of rats tissues under experimental toxic hepatitis

   


1. Voronezh State University
Type: Experimental/clinical study
DOI: 10.18097/pbmc20105604490      UDK: 577.15:577.334:616.36-002      PubMed Id: 21032899
Year: 2010 vol: 56  issue:4  pages: 490-498
Abstract: The effect of citrate free-radical oxidation intensity and aconitate hydratase, superoxide dismutase and catalase activities in liver and blood serum of rats with experimental toxic hepatitis has been investigated. Citrate administration to rats with hepatitis decreased biochemiluminescence parameters and conjugated diene content in rats tissues, increased under conditions of CCl4-induced liver damage. At the same time aconitase activity, decreased at the pathology, increases. The superoxide dismutase and catalase activities increased in at experimental toxic hepatitis, tended towards control values after citrate administration.
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Reference: Safonova O.A., Popova T.N., Saidi L., Citrate influence on oxidative status of rats tissues under experimental toxic hepatitis, Biomeditsinskaya khimiya, 2010, vol: 56(4), 490-498.
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