Study of activity of enzymes of antioxidant system of blood at HIV infection

   


1. Military medical clinical center of South region
2. Mechnikov Odessa National University
Type: Experimental/clinical study
DOI: 10.18097/pbmc20105605596      UDK: 616.98:578.828.6-07:616.15-008.93      PubMed Id: 21254630
Year: 2010 vol: 56  issue:5  pages: 596-601
Abstract: HIV infection is accompanied by activation of lipid peroxidation, oxidative modification of lipoprotein complexes, and a decrease in activity of antioxidant enzymes (superoxide dismutase (SOD), catalase and glutathione peroxidase (GP)) in blood serum. A significant increase of glutathione reductase observed under these conditions is considered as a function of the antioxidant defence. These changes were already seen at early (symptomless) stages of this disease, however, at manifested forms they were more pronounced.
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Reference: Kostyushov V.V., Bokal I.I., Petrov S.A., Study of activity of enzymes of antioxidant system of blood at HIV infection, Biomeditsinskaya khimiya, 2010, vol: 56(5), 596-601.
This paper is also available as the English translation:10.1134/S1990750811020041
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