Mitochondrial disfunction in Parkinson's disease


1. Institute of Biomedical Chemistry
Type: Review
DOI: 10.18097/pbmc20115703246      UDK: 616-009      PubMed Id: 21863741
Year: 2011 vol: 57  issue:3  pages: 246-281
Abstract: Mitochondrial structural and functional abnormalities in Parkinson's disease and experimental animal models of this pathology are described. Special attention is paid to the inactivation of mitochondrial enzymes, mutations in mitochondrial and nuclear DNA, and genomic and proteomic research of mitochondrial proteins in Parkinson's disease and experimental parkinsonism of animals.
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Reference: Buneeva O.A., Medvedev A.E., Mitochondrial disfunction in Parkinson's disease, Biomeditsinskaya khimiya, 2011, vol: 57(3), 246-281.
This paper is also available as the English translation:10.1134/S1990750811040032