The influence of сhromium chloride consumption on peroxidation processes and activity of antioxidant defence in rat tissues

   


1. Institute of Animal Biology NAAS
Type: Experimental/clinical study
DOI: 10.18097/pbmc20125804418      UDK: 546.76:678.048      PubMed Id: 23413686
Year: 2012 vol: 58  issue:4  pages: 418-428
Abstract: The supplementation of a standart vivarium food with 200 mg/kg CrCl3×6H2O caused an increase in chromium content and a decrease in hydroperoxide and TBARS in most tissues examined. Also in all organs and tissues of rats the activity of glutathione peroxidase, glutathione reductase and catalase incresed at action of chromium increased. In brain and kidneys the level of reduced glutathione increased. Superoxide dismutase activity was significantly higher in heart and skeletal muscles of animals and equal in lungs and liver, and in other organs - brain, kidneys and spleen in animals of the studied group the enzyme activity was lower compared to animals of control group. These results demonstrate the regulatory influence of chromium on free radical process in rat tissues.
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Reference: Iskra R.Ya., Yanovych V.G., The influence of сhromium chloride consumption on peroxidation processes and activity of antioxidant defence in rat tissues, Biomeditsinskaya khimiya, 2012, vol: 58(4), 418-428.
This paper is also available as the English translation:10.1134/S1990750813030062
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