Abstract: It was shown that modification of screen printed graphite electrodes with gold nanoparticles (AuNPs) decorated Pb nanowires (PbNWs) demonstrates the enhancement of sensor’s analytical characteristics such as effective surface area, electro catalytic properties and heterogeneous electron transfer kinetics. The reason for such improvement may be the synergistic effect of AuNPs and PbNWs. Nanowires ensembles on electrode surface were employed for the detection of hemeproteins cytochrome P450 2B4, cytochrome c , and cardiac myoglobin in human plasma. Composite materials based on nanoparticles with different dimentions (3D three dimensional gold nanoparticles and 1D one dimensional Pb nanowires make it possible to construct biosensors with low detection limit of proteins.
Reference: Shumyantseva V.V., Bulko T.V., Suprun E.V., Archakov A.I., Electrochemical sensor systems based on one dimensional (1D) nanostructures for analysis of bioaffinity interactions, Biomeditsinskaya khimiya, 2013, vol:
21. Altnder S., Scharbotough P., Peto V., Rayner M., Lean J., Luengo-Fernandez R. (2008) European cardiovascular disease statistics, 2008 edition, London: British Heart Foundation. Scholar google search