Integrins as a potential target for targeted anticancer therapy

   


1. Orekhovich Institute of Biomedical Chemistry
Type: Review
DOI: 10.18097/pbmc20135903239      UDK: 577.24      PubMed Id: 23987064
Year: 2013 vol: 59  issue:3  pages: 239-248
Abstract: The review briefly summarizes information of structure of integrins and their involvement in the development and malignant progression of tumors. Special attention is paid to approaches based on modification of functional properties of integrins that prevent/antagonize tumor growth and progression; these approaches developed in modern experimental biology have certain perspective in clinical application.
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Reference: Berman A.E., Kozlova N.I., Morozevich G E., Integrins as a potential target for targeted anticancer therapy, Biomeditsinskaya khimiya, 2013, vol: 59(3), 239-248.
This paper is also available as the English translation:10.1134/S1990750812030031
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