Metabolic profiling of human blood

   


1. Orekhovich Institute of Biomedical Chemistry, Russian Academy of Medical Sciences
Type: Review
DOI: 10.18097/pbmc20146003281      UDK: 577.152.3      PubMed Id: 25019391
Year: 2014 vol: 60  issue:3  pages: 281-294
Abstract: Metabolomics is a novel “omics” branch of science intended for studying a comprehensive set of low molecular weight substances (metabolites) of various biological objects. Metabolite profiles represent a molecular phenotype of biological systems and reflect information encoded at the genome level and realized at the transcriptome and proteome levels. Analysis of human blood metabolic profile is universal and promising tool for clinical applications because it is a sensitive measure of both endogenous and exogenous (environmental) factors affected on the patient's organism. Technical implementation of metabolic profiling of blood and statistic analysis of metabolite profiles for effective diagnostics and risk assessments of diseases are discussed in this review.
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Reference: Trifonova O.P., Lokhov P.G., Archakov A.I., Metabolic profiling of human blood, Biomeditsinskaya khimiya, 2014, vol: 60(3), 281-294.
This paper is also available as the English translation:10.1134/S1990750813030128
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