Glycine receptors in nervous tissue and their functional role


1. Polessky State University
2. Institute of Physiology of NAS of Belarus
Type: Review
DOI: 10.18097/pbmc20146004403      UDK: 612.014.3:612.8+577.112.382.2:576.314.6      PubMed Id: 25249524
Year: 2014 vol: 60  issue:4  pages: 403-415
Abstract: The literature data on glycine metabolism in neural tissue, mitochondrial Gly-cleaving system, Gly-catching system in neural and glial cells are summarized. The peculiarities of localization and distribution of specific glycine receptors and binding-sites in nervous tissue of mammals are described. Four types of glycine-binding receptors are described: own specific glycine receptor (Gly-R), ionotropic receptor, which binds N-methyl-D-aspartate selectively (NMDA-R), and ionotropic receptors of g-aminobutyrate (GABA A -R, GABA С -R). The feutures of glycine effects in neuroglial cultures are discussed
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Reference: Nikandrov V.N., Balashevich T.V., Glycine receptors in nervous tissue and their functional role, Biomeditsinskaya khimiya, 2014, vol: 60(4), 403-415.
This paper is also available as the English translation:10.1134/S1990750813030104