Extracting and study of biochemical properties of thiamine pyrophosphokinase from non-malignant and tumor tissue of myometrium

   


1. Mechnikov Odessa National University
Type: Clinical study
DOI: 10.18097/pbmc20146005602      UDK: 577.152.344:577.15.072      PubMed Id: 25386891
Year: 2014 vol: 60  issue:5  pages: 602-607
Abstract: The method of extraction and purification of thiamine pyrophosphokinase from non-malignant and tumor tissue of myometrium has been elaborated. Kinetic characteristics of T-kinase from non-malignant and tumor tissue of women myometrium have been studied. It has been shown, that malignization of myometrium is accompanied by a decrease in affinity of thiamine pyrophosphokinase from tumor to thiamine and by an increase in sensitivity of the enzyme from tumor to thiochrome.
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Reference: Orishaka O.V., Vovchuk I.L., Petrov S.A., Extracting and study of biochemical properties of thiamine pyrophosphokinase from non-malignant and tumor tissue of myometrium, Biomeditsinskaya khimiya, 2014, vol: 60(5), 602-607.
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