Abstract: Physiological plasminogen activators of tissue and urokinase type (serine proteinases) are effective thrombolytic agents. Research and development of their novel forms contributed to progress of thrombolytic therapy, advanced treatment of acute coronary syndrome and a marked decrease in the lethal index.
Reference: Maksimenko A.V., Thrombolysis with plasminogen activators: use and research of serine proteinases, promise and actuality, Biomeditsinskaya khimiya, 2014, vol:
1. Widimsky P., Coram R., Abou-Chebl A. (2014) Eur. Heart J., 35, 147-155. CrossRef