Oxidative stress in adipose tissue as a primary link in pathogenesis of insulin resistance

   


1. Siberian State Medical University, Тоmsk, Russia
Type: Review
DOI: 10.18097/PBMC20166201014      UDK: 577.152.1:577.175.722:577.125.32:616-092      PubMed Id: 26973182
Year: 2016 vol: 62  issue:1  pages: 14-21
Abstract: Obesity is a leading risk factor of diabetes mellitus type 2, impairments of lipid metabolism and cardiovascular diseases. Dysfunctions of the accumulating weight of the visceral fat are primarily linked to pathogenesis of systemic insulin resistance. The review considers modern views about biochemical mechanisms underlying formation of oxidative stress in adipocytes at obesity, as one of key elements of impairments of their metabolism triggering formation of systemic insulin resistance.
Download PDF:
Reference: Kuzmenko D.I., Udintsev S.N., Klimentyeva T.K., Serebrov V.Yu., Oxidative stress in adipose tissue as a primary link in pathogenesis of insulin resistance, Biomeditsinskaya khimiya, 2016, vol: 62(1), 14-21.
This paper is also available as the English translation:10.1134/S1990750816030100
References
 2017(Vol:63)
 2016(Vol:62)
 2015(Vol:61)
 2014(Vol:60)
 2013(Vol:59)
 2012(Vol:58)
 2011(Vol:57)
 2010(Vol:56)
 2009(Vol:55)
 2008(Vol:54)
 2007(Vol:53)
 2006(Vol:52)
 2005(Vol:51)
 2004(Vol:50)
 2003(Vol:49)