The role of vascular endothelial growth factor in the regulation of development and functioning of the brain: new target molecules for pharmacotherapy

   


1. Voyno-Yasenetski Krasnoyarsk State Medical Academy, Krasnoyarsk, Russia
2. Berzon Krasnoyarsk Regional Clinical Hospital N 20, Krasnoyarsk Russia
Type: Review
DOI: 10.18097/PBMC20166202124      UDK: 616-092.4      PubMed Id: 27143368
Year: 2016 vol: 62  issue:2  pages: 124-133
Abstract: Vascular endothelial growth factors (VEGFs) have been shown to participate in atherosclerosis, arteriogenesis, cerebral edema, neuroprotection, neurogenesis, angiogenesis, postischemic brain and vessel repair. Most of these actions involve VEGF-A and the VEGFR-2 receptor. VEGF signaling pathways represent an important potential for treatment of neurological diseases affecting the brain
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Reference: Roslavtceva V.V., Salmina A.B., Prokopenko S.V., Pozhilenkova E.A., Kobanenko I.V., Rezvitskaya G.G., The role of vascular endothelial growth factor in the regulation of development and functioning of the brain: new target molecules for pharmacotherapy, Biomeditsinskaya khimiya, 2016, vol: 62(2), 124-133.
This paper is also available as the English translation:10.1134/S1990750816040053
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