Basic carboxypeptidases of blood: significance for coagulology


1. Russian Research Institute of Haematology and Transfusiology, Saint Petersburg, Russia
Type: Review
DOI: 10.18097/PBMC20166202141      UDK: 612.128:612.115.1:612.115      PubMed Id: 27143370
Year: 2016 vol: 62  issue:2  pages: 141-149
Abstract: This review considers the basic metallocarboxypeptidases of human blood and their role in coagulologic disorders. In includes information on the history of the discovery and biological characteristics of potential enzymes-regulators of the fibrinolytic process: carboxypeptidase U and carboxypeptidase N. Certain attention is paid to the biochemical mechanisms and the main modern concepts of the antifibrinolytic effects of these enzymes
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Reference: Timofeev А.V., Basic carboxypeptidases of blood: significance for coagulology, Biomeditsinskaya khimiya, 2016, vol: 62(2), 141-149.
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