В обзоре рассмотрены свойства цинковых металлопротеиназ, принадлежащих к семейству астацина. Эти ферменты обладают ариламидазной активностью, нехарактерной для металлопротеиназ. Особое внимание уделено физиологическим функциям протеиназ семейства астацина и влиянию доменного состава и посттрансляционных модификаций на активность и стабильность этих ферментов.
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