Experimental and literary data on the peculiarities of complement alternative pathway (APC) self-regulation and regulation are reviewed. There is a discussion of the methods of APC evaluation, including a new one, called complement hemolytical capacity. It is shown that the duration of complement-dependent hemolysis lag-period is limited by factor D concentration. The phenomenon of acceleration of APC-dependent hemolysis by membranes of lysed cells is described. The latter is an evidence of APC functioning in the mode of double amplification.
Galebskaya L.V. (1998) New approaches in the study of complement alternative pathway self-regulation. Voprosy Meditsinskoi Khimii, 44(5), 501-505.
et al. New approaches in the study of complement alternative pathway self-regulation // Voprosy Meditsinskoi Khimii. - 1998. - V. 44. -N 5. - P. 501-505.
et al., "New approaches in the study of complement alternative pathway self-regulation." Voprosy Meditsinskoi Khimii 44.5 (1998): 501-505.
Galebskaya, L. V. (1998). New approaches in the study of complement alternative pathway self-regulation. Voprosy Meditsinskoi Khimii, 44(5), 501-505.
