Aminopeptidases in human leukemic lymphoid cells

Gureeva T.A.; Golubeva N.V.; Lubkova O.N.

VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Aminopeptidases in human leukemic lymphoid cells

Gureeva T.A., Golubeva N.V., Lubkova O.N.

PubMed Id: 10547880

Year: 1999 Volume: 45 Issue: 4 Pages: 309-313

Aminopeptidase activity in lymphoid cells of patients with various lymphoproliferative diseases was studied. The enzyme activity was detected in lysates of all leukemic B- and T-cells. The lymphoid cells contained aminopeptidases of at least two classes: metallo- and SH-dependent enzymes. The SH-dependent aminopeptidase with pH optimum 8.5-9.0 was revealed in lymphoid cells for the first time, and it seems to belong to a poorly studied aminopeptidase family.

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Keywords: Aminopeptidases, leukemic lymphoid cells

Citation:

Gureeva, T. A., Golubeva, N. V., Lubkova, O. N. (1999). Aminopeptidases in human leukemic lymphoid cells. Voprosy Meditsinskoi Khimii, 45(4), 309-313.

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