Tissue-specific nucleoprotein complexes

Riadnova I.Yu.; Shataeva L.K.; Khavinson V.Kh.

VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Tissue-specific nucleoprotein complexes

Riadnova I.Yu.¹, Shataeva L.K.², Khavinson V.Kh.¹

1. St.Petersburg Institute of Bioregulation and Gerontology, North-Western Department of the Russian Academy of Medical Sciences
2. Institute of Macromolecular Compounds, Russian Academy of Sciences

PubMed Id: 10802888

Year: 2000 Volume: 46 Issue: 1 Pages: 62-71

A method of isolation of native nucleorprotein complexes from cattle cerebral cortex, thymus, and liver was developed. Compositions of these complexes were studied by means of gel-chromatography and ion-exchange chromatography. These preparations were shown to consist of several fractions of proteins and their complexes differ by molecular mass and electro-chemical properties. Native nucleoprotein complexes revealed high tissue specific activity, which was not species-specific.

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Keywords: nucleorprotein complexes, component composition, gel-chromatography, gangho - specific activity

Citation:

Riadnova, I. Yu., Shataeva, L. K., Khavinson, V. Kh. (2000). Tissue-specific nucleoprotein complexes. Voprosy Meditsinskoi Khimii, 46(1), 62-71.

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2002 (vol 48)