Review considers perspectives and the main advantages in the development of the approaches to gene therapy in organ and cell transplantology. The methods of prevention in allo- and xenotransplantation by the inhibition of the recipient immune system, and the problem of specific tolerance to graft in host organism creation by mixed antigenic chimerism making by means of gene therapy methods are discussed.
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Dolguikh M.S. (2004) Gene-cell therapy and possibilities of its application in transplantology for prevention of transplantant rejection. Biomeditsinskaya Khimiya, 50(1), 3-24.
et al. Gene-cell therapy and possibilities of its application in transplantology for prevention of transplantant rejection // Biomeditsinskaya Khimiya. - 2004. - V. 50. -N 1. - P. 3-24.
et al., "Gene-cell therapy and possibilities of its application in transplantology for prevention of transplantant rejection." Biomeditsinskaya Khimiya 50.1 (2004): 3-24.
Dolguikh, M. S. (2004). Gene-cell therapy and possibilities of its application in transplantology for prevention of transplantant rejection. Biomeditsinskaya Khimiya, 50(1), 3-24.
References
Guillot С, Le Mauff B., Cuturi М.С., Anegon I. (2000) Gene Therapy, 7, 14- 19. Scholar google search
Шумаков В.И., Левицкий Э.Р., Порядин К. Ф., Алексеев Л.П. (1982) Синдром отторжения при трансплантации почки. Москва, Медицина. Scholar google search
Aran J- M., Filial С, EstivillX. (1999) Transplant.Proceedings., 31, 2228- 222. Scholar google search
Fry J. W., Wood K.J. (1999) Exp. Rev. Mol. Med., Cambridge University Press ISSN, www- ermm.cbcu.cam.ac.uk. Scholar google search
Giannoukakis N.. Thomson A. W., Robbins P.D. (1999) Gene Therapy, 6, 1499- 1511. Scholar google search
Zwacka R.M., Zhou W.H., Zhang Y.L. et al. (1998) Nature Med., 4, 698- 704. Scholar google search
Madsen J.C, Superina R.A., Wood K.J., Morris P. (1988) Nature, 332, 161- 164. Scholar google search
Sykes M., Sachs D.H., Nienhuis A. W. et al. (1993) Transplantation, 55, 197- 202. Scholar google search
Emery D. W., Sablinski T, Shimada H. et al. (1997) Transplantation, 64, 1414- 1423. Scholar google search
Knechtle S.J., WangJ., Graeb Ch. et al. (1997) J.ImmunoL, 159, 152- 158. Scholar google search
Olthoff K.M., Judge T.A., Gelman A.E. et al. (1998) Nature.Med., 4, 194- 200. Scholar google search
Gainer A.L., Suarez- Pinzon W.L., Min W.P.et al. (1998) TransplantProc, 30, 534. Scholar google search
Lu L, Gambotto A., Lee We. et al. (1999) Gene Therapy, 6, 554- 563. Scholar google search
Qin L, Chavin K.D., Ding Y. et al. (1995) Transplantation, 59, 809- 816. Scholar google search
