Modern concepts concerning iron metabolisms in the body, its circulation, involvement into free radical processes and lipid peroxidation (LP) are reviewed. Spetial attention is paid to cytotoxic effects, Fe2+ influence on lipid peroxidation, its role in multiple organ failure development in critical states. Iron ion can be bound by desferal, which may be effectively used for intensive care of critical states.
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Keywords: iron metabolism, lipid peroxidation, desferal
Citation:
Orlov Yu.P., Dolgich V.T. (2007) Iron metabolism in biological systems (biochemical, pathophysiological and clinical perspectives). Biomeditsinskaya Khimiya, 53(1), 25-38.
Orlov Yu.P. et al. Iron metabolism in biological systems (biochemical, pathophysiological and clinical perspectives) // Biomeditsinskaya Khimiya. - 2007. - V. 53. -N 1. - P. 25-38.
Orlov Yu.P. et al., "Iron metabolism in biological systems (biochemical, pathophysiological and clinical perspectives)." Biomeditsinskaya Khimiya 53.1 (2007): 25-38.
Orlov, Yu. P., Dolgich, V. T. (2007). Iron metabolism in biological systems (biochemical, pathophysiological and clinical perspectives). Biomeditsinskaya Khimiya, 53(1), 25-38.
