The new fluorogenic hexapeptide substrate CMC-Ala-Gly-Gly-Trp-Phe-Arg was used as substrate for endothelin-converting enzyme (ECE), angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP). The specific inhibitors lisinopril (ACE) and thiorphan (NEP) were used for identification of these enzyme activities.
Gureeva T.A., Kugaevskaya E.V., Pozdnev V.F., Prozorovskiy V.N., Elisseeva Yu.E., Solovyeva N.I. (2007) Study of substrate specificity of a new peptide substrate of endothelin converting enzyme. Biomeditsinskaya Khimiya, 53(2), 172-180.
Gureeva T.A. et al. Study of substrate specificity of a new peptide substrate of endothelin converting enzyme // Biomeditsinskaya Khimiya. - 2007. - V. 53. -N 2. - P. 172-180.
Gureeva T.A. et al., "Study of substrate specificity of a new peptide substrate of endothelin converting enzyme." Biomeditsinskaya Khimiya 53.2 (2007): 172-180.
Gureeva, T. A., Kugaevskaya, E. V., Pozdnev, V. F., Prozorovskiy, V. N., Elisseeva, Yu. E., Solovyeva, N. I. (2007). Study of substrate specificity of a new peptide substrate of endothelin converting enzyme. Biomeditsinskaya Khimiya, 53(2), 172-180.
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