Using actinomycins as an example, the possibility of increasing the anti-tumor activity of heterocyclic antibiotics due to photo-activation, has been studied. In model experiments with solutions of actinomycins, it was showed that actinomycins have a significant photochemical activity (of its own), changing by the binding to DNA in solution or in tumor cells. Photo-destruction of HeLa cells and the release of the antibiotic were observed.
Vekshin N.L. (2009) Patent RF number 2372073, Delivery of heterocyclic antibiotics to cancer cells using nano-nucleotide farmakosom. Scholar google search
