1. Lomonosov Moscow State University; Advanced Technologies Center, Moscow 2. Lomonosov Moscow State University; Advanced Technologies Center, Moscow;“RPE Immunotek”, Moscow 3. Lomonosov Moscow State University; Advanced Technologies Center, Moscow;RPE Advanced Technologies Center, Moscow
We present new approaches to improve the efficiency of DNA by scanning probe microscopy using a highly specific hybridization on affine surfaces and nanostructures of gold as a labels. Scanning probe microscopy allows to register of individual acts of hybridization by the detection of gold labels on the surface affinity followed by automatic calculation of the total.
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Keywords: scanning probe microscopy, analysis and image processing, DNA-biosensor, highly specific hybridization, nanoparticles
Citation:
Dubrovin E.V., Presnova G.V., Rubtsova M.Yu., Grigorenko V.G., Ivanin A.I., Egorov A.M., Yaminsky I.V. (2014) Implementation of scanning probe microscopy for the solution of molecular diagnostics tasks. Biomeditsinskaya Khimiya, 60(5), 543-547.
Dubrovin E.V. et al. Implementation of scanning probe microscopy for the solution of molecular diagnostics tasks // Biomeditsinskaya Khimiya. - 2014. - V. 60. -N 5. - P. 543-547.
Dubrovin E.V. et al., "Implementation of scanning probe microscopy for the solution of molecular diagnostics tasks." Biomeditsinskaya Khimiya 60.5 (2014): 543-547.
Dubrovin, E. V., Presnova, G. V., Rubtsova, M. Yu., Grigorenko, V. G., Ivanin, A. I., Egorov, A. M., Yaminsky, I. V. (2014). Implementation of scanning probe microscopy for the solution of molecular diagnostics tasks. Biomeditsinskaya Khimiya, 60(5), 543-547.
