Lipid peroxidation (LPO) in the heart of adult (10-12 month) and old (22-25 month) Wistar male rats was investigated during immobilized stress. Immobilization of rats was accompanied by increasing the concentration of all studied LPO intermediates in the myocardium of both age groups. Accumulation of LPO products in old rat hearts was considerably higher than in adult ones. Dimethyl sulfoxide injection limited stress-induced stimulation of LPO. There were age related variations in efficiency of this antioxidant effect on the heart during immobilized stress.
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Shvets V.N., Davydov V.V. (2003) Lipid peroxidation in the heart of adult and old rats during the immobilized stress. Biomeditsinskaya Khimiya, 49(2), 117-121.
Shvets V.N. et al. Lipid peroxidation in the heart of adult and old rats during the immobilized stress // Biomeditsinskaya Khimiya. - 2003. - V. 49. -N 2. - P. 117-121.
Shvets V.N. et al., "Lipid peroxidation in the heart of adult and old rats during the immobilized stress." Biomeditsinskaya Khimiya 49.2 (2003): 117-121.
Shvets, V. N., Davydov, V. V. (2003). Lipid peroxidation in the heart of adult and old rats during the immobilized stress. Biomeditsinskaya Khimiya, 49(2), 117-121.
References
Сауля А.К., Меерсон Ф.З. (1990) Постстрессорное нарушение функции миокарда. Кишинев: Штиинца. Scholar google search
Ceremuzinski L., Barcikowski В., Lewicki Z. (1991) Exp.Pathol., 43, 213 - 220. Scholar google search
Ytrehus К., Hegstad A.C. (1991) Acta Physiol.Scand., 599, 81- 91. Scholar google search
Швец В.К., Давыдов В. В. (1992) Биохимия стресса и пути повышения эффективности лечения заболеваний стрессорной природы. Запорожье, издат. ЗГМУ, с.64- 67. Scholar google search
Стальная И.Д. (1977) Современные методы в биохимии. М.:Медицина, с. 63- 64. Scholar google search
Kates М. (1977) Techniques of Lipidology. Isolation, Analysis and Identifica tion of Lipids. Amsterdam, London: American Elsevier Publishing Co., 320 p. Scholar google search
Muller G., Fruhant A., Mathias B. (1986) Z. Gezamte. Urn. Med. und Grenzgeb., 41, 673- 676. Scholar google search
