Antioxidants in malignant human and experimental tumors

   
Nikiforova N.V.1, Berman A.E.2

1. Institute of Urology, Ministry of Public Health Care of Russian Federation
2. Orekhovich Institute of Biomedical Chemistry RAMS
Section: Review
PubMed Id: 14564734
Year: 2003  Volume: 49  Issue: 3  Pages: 250-262
This review is devoted to the role of low molecular weight antioxidants and antioxidant enzymes in cancerogenesis. The data are analyzed on accumulation of lipid-soluble and water-soluble antioxidants in a number of malignant human and experimental tumors especially in the renal cell carcinoma tissues. A possibility is discussed concerning the pro- and anticancerogenic effects of the abundant tumor content of antioxidants. Implication of antioxidants in tumor resistance to chemotheraputic drugs and ionazing radiation is discussed as well.
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Citation:

Nikiforova, N. V., Berman, A. E. (2003). Antioxidants in malignant human and experimental tumors. Biomeditsinskaya Khimiya, 49(3), 250-262.
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