Myelin oligodendrocyte glycoprotein (MOG) is a myelin-specific protein of the central nervous system (CNS). It is a member of the immunoglobulin superfamily. The contents of this protein in oligodendrogliocyte membrane is very low (approximately 0.1% total proteins). functions of MOG are still unknown. It is considered that MOG is an autoantigen capable to produce a demyelinating multiple sclerosis-like disease in experimental animals. The structure, membrane topology, putative functions and role in demyelinating diseases are considered in this review.
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Chekhonin V.P., Semenova A.V., Gurina O.I., Dmitrieva T.B. (2003) Myelin oligodendrogliocyte glycoprotein the structure, functions, role in pathogenesis of demyelinating diseases. Biomeditsinskaya Khimiya, 49(5), 411-423.
Chekhonin V.P. et al. Myelin oligodendrogliocyte glycoprotein the structure, functions, role in pathogenesis of demyelinating diseases // Biomeditsinskaya Khimiya. - 2003. - V. 49. -N 5. - P. 411-423.
Chekhonin V.P. et al., "Myelin oligodendrogliocyte glycoprotein the structure, functions, role in pathogenesis of demyelinating diseases." Biomeditsinskaya Khimiya 49.5 (2003): 411-423.
Chekhonin, V. P., Semenova, A. V., Gurina, O. I., Dmitrieva, T. B. (2003). Myelin oligodendrogliocyte glycoprotein the structure, functions, role in pathogenesis of demyelinating diseases. Biomeditsinskaya Khimiya, 49(5), 411-423.
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