1. Moscow Clinical hospital N29, Orekhovich Institute of Biomedical Chemistry, RAMS 2. Russian State medical University 3. Moscow Clinical hospital N29 4. State Research Center of Applied Microbiology, Ministry of Public Health
Sera of 80 patients with pyodermias of varius etiology were analysed for interferon-g (IF-g), antiinterferon autoantibodies (IF-a-AB), corresponding antiidiotypic antibodies (IF-AIAB) and the ratio IF-a-AB/IF-AIAB using ELISA assay. There was no correlation between serum IF-g and IF-a-AB. Progression of this disease was characterized by an increase of serum IF-a-AB and a decrease of IF-AIAB. Prolonged duration of this disease also caused the decrease of serum anti IF-a-AB and IF-AIAB. The ratio of IF-a-AB/IF-AIAB increased with severity and duration of this disease.
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Morosov S.G., Volkova E.N., Gnedenko B.B., Protsenko A.N., Fedyukin V.S. (2003) Interferon-gamma, idiotypic and antiidiotypic interferon autoantibodies at pyodermias of various etiology. Biomeditsinskaya Khimiya, 49(6), 613-622.
Morosov S.G. et al. Interferon-gamma, idiotypic and antiidiotypic interferon autoantibodies at pyodermias of various etiology // Biomeditsinskaya Khimiya. - 2003. - V. 49. -N 6. - P. 613-622.
Morosov S.G. et al., "Interferon-gamma, idiotypic and antiidiotypic interferon autoantibodies at pyodermias of various etiology." Biomeditsinskaya Khimiya 49.6 (2003): 613-622.
Morosov, S. G., Volkova, E. N., Gnedenko, B. B., Protsenko, A. N., Fedyukin, V. S. (2003). Interferon-gamma, idiotypic and antiidiotypic interferon autoantibodies at pyodermias of various etiology. Biomeditsinskaya Khimiya, 49(6), 613-622.
Полетаев А.Б., Морозов С.Г. (2002) Регуляторная метасистема. Иммунонейроэндокринная регуляция гомеостаза. М.: Медицина. Scholar google search
Bendtzen К., Svenson M., Jonsson V., Hippe E. (1990) Immunol. Today, 11, 167- 169. Scholar google search
Bakhiet M., Diab A., Mahamustafa, Jiezhu, Lindqvist L., Link H. (1997) Infect. Immun., 65, 3300- 3303. Scholar google search
Хромцов М.М. (2000) Вестн. Смоленской мед. академии, 4, 95- 97. Scholar google search
Морозов С.П. (1997) Антитела к белкам нервной ткани при нервных и психических заболеваниях (иммунохимическое и клинико- иммунологическое исследование). Дисс... докт. мед. наук. Москва. Scholar google search
Чурилов Л.П. (1988) В кн.: Иммунол. регуляция клеточных функций. Л.: Медицина, с. 30- 43. Scholar google search
Elkarim R., Granert С., Lindquist L., Link K., Bakhiet M. (1999) Infect. Immun., 67, 3051- 3054. Scholar google search
Elkarim R.A., Dahle C., Mustafa M., Press R., Zou L.P., Ekerfelt C., Ernerudh I., Link H., Bakhiet M. (1998) Clin. Immunol. Immunopathol., 88, 241- 248. Scholar google search
Madariaga L., Amurrio С., Martin G., Garcia- Cebrian E., Bicandi J., Lardelli P., Suarez M.D., Cisterna R. (1998) Int. J. Tuberc. Lang Die, 2, 62- 68. Scholar google search
Кульберг А.Я. (1986) Регуляция иммунного ответа. М.: Медицина. Scholar google search
