RFLP-analysis was made for 30 human DNA samples. The ability of application of restriction endonucleases Acc65I and Bst2UI to find point mutation C481T in NAT2 gene has been demonstrated for the first time. Variants of these enzymes application are discussed.
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Nikishina M.V., Akishev A.G., Makarova S.I., Vavilin V.A., Degtyarev S.Kh., Lyakhovich V.V. (2004) Application restriction endonucleases Bst2UI and Acc65I to find kpn I - polymorphism in NAT2 gene. Biomeditsinskaya Khimiya, 50(3), 269-272.
Nikishina M.V. et al. Application restriction endonucleases Bst2UI and Acc65I to find kpn I - polymorphism in NAT2 gene // Biomeditsinskaya Khimiya. - 2004. - V. 50. -N 3. - P. 269-272.
Nikishina M.V. et al., "Application restriction endonucleases Bst2UI and Acc65I to find kpn I - polymorphism in NAT2 gene." Biomeditsinskaya Khimiya 50.3 (2004): 269-272.
Nikishina, M. V., Akishev, A. G., Makarova, S. I., Vavilin, V. A., Degtyarev, S. Kh., Lyakhovich, V. V. (2004). Application restriction endonucleases Bst2UI and Acc65I to find kpn I - polymorphism in NAT2 gene. Biomeditsinskaya Khimiya, 50(3), 269-272.
References
Hein D. V, Grant DM, Sim E. (2000) Pharmacogenetics, 10, 291- 292. Scholar google search
Bandmann О., Vaughan J.R., Holmans P., Marsden C.D., WoodN. W. (2000) Mov. Disord., 15, 30- 35. Scholar google search
Hein D.W., Doll M.A., Fretland A.J., Leff M.A., Webb S.J., Xiao G.H., Devanaboyin U.S., Nangju N.A., Fend Y. (2000) Cancer Epidemiol. Biomarkers Prev., 9, 29- 42. Scholar google search
Lee E.J., Zhao В., Seow- Choen F. (1998) Pharmacogenetics., 8, 513- 517. Scholar google search
Kunkel L.M., Smith K.D., Boyer S.H., Bordgaonkar D.S., Wachtel S.S., Miller O.J., Bred W.R., Jones H. W., RaryJ.M. (1977) Proc. Natl. Acad. Sci. USA, 74, 1245- 1249. Scholar google search
Hickman D., Sim E. (1991) Biochem. Pharmacol., 42, 1007- 1014. Scholar google search
