Phospholipid spectrum of blood serum in diagnostic of different stages of combined hepatic viral-alcoholic damage.

   
Makarov V.K.1

1. Tver State Medical Academy
Section: Experimental/Clinical Study
PubMed Id: 15628600
Year: 2004  Volume: 50  Issue: 5  Pages: 498-501
Phospholipid spectrum indexes at different stages of a viral-alcoholic damage of liver were investigated in 30 HBsAg carriers with alcoholism, 40 patients with chronic viral hepatitis В and 20 patients with hepatic cirrhosis. The level of lysophosphatidyl choline and lysophosphatidyl etanolamine was progressively depressed from the stage of HBsAg carriage to the stages of chronic hepatitis and cirrhosis. The content of total lipids at the patients with liver cirrhosis was lower than in HBsAg carriers and patients with chronic hepatitis whereas phosphatidyl choline was higher. The phospholipid spectrum indexes can be recommended as an additional method for differential diagnostics of the stage of chronic hepatitis from stage of liver cirrhosis.
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Makarov V.K. (2004) Biomeditsinskaya khimiya, 50(5), 498-501.
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