1. Kharkov National University 2. Institute of Children and Adolescent Health Protection, Ukrainian Academy of Medical Sciences 3. V.N. Orekhovich Institute of Biomedical Chemistry, Russian Academy of Medical Sciences 4. Zaporozhye State Medical University
The antioxidant action of the extract from Aronia melanocarpa leaves on the brain was investigated. The intraperitoneal injection of extract in the dose of 0.2 g/kg prevented manifestations of oxidative stress in the brain induced by immobilization of rats. In vitro experiments revealed that the extract decreased intensity of ascorbate - and Н2О2 -induced lipid and protein peroxidation in the brain homogenates. The most effect of the extract on ascorbate - induced lipid peroxidation was found in the postmitochondrial fraction of brain homogenate.
Download PDF:
Citation:
Suvorova I.N., Davydov V.V., Prozorovskiy V.N., Shvets V.N. (2005) Peculiarity of extract from Aronia melanocarpa leaves antioxidant action for the brain. Biomeditsinskaya Khimiya, 51(1), 66-71.
Suvorova I.N. et al. Peculiarity of extract from Aronia melanocarpa leaves antioxidant action for the brain // Biomeditsinskaya Khimiya. - 2005. - V. 51. -N 1. - P. 66-71.
Suvorova I.N. et al., "Peculiarity of extract from Aronia melanocarpa leaves antioxidant action for the brain." Biomeditsinskaya Khimiya 51.1 (2005): 66-71.
Suvorova, I. N., Davydov, V. V., Prozorovskiy, V. N., Shvets, V. N. (2005). Peculiarity of extract from Aronia melanocarpa leaves antioxidant action for the brain. Biomeditsinskaya Khimiya, 51(1), 66-71.
References
Sime W.E., Buel J.C. (1980) J. Cardiovasc. Pulm. Techn, 8(5) , 27-41. Scholar google search
Судаков К.В., Улъянинский Л.С. (1980) Вестник АМН СССР, 34(11) , 37-41. Scholar google search
Меерсон Ф.3. (1984) Патогенез и предупреждение стрессорныхи ишемических повреждений сердца.-М.:Медицина. Scholar google search
Kovacs R., Jwanek L., Stankovicova Т., Svec R. (1996) Pharmazie., 51(1) , 51-53. Scholar google search
Ипатова O.M., Прозоровский В.Н. Патент на изобретение РФ №2171111 от 05.05.2000г . "Экстракт листьев Аронии, обладающий биологической активностью и способ его получения". Scholar google search
Стальная И.Ц. (1977) Современные методы в биохимии. М.Медицина, 63-64. Scholar google search
Rice-Evans С.А., Diplock A.I., Symons M.C.R. (1991) Laboratory techniques in biochemistry and molecular biology: techniques in free radical research. -London. Scholar google search
