Peculiarities of free radical antioxidant statute in patients with systemic lupus erythematosus and rheumatoid arthritis

   
Podoprigorova V.G.1 , Bobilev A.A.1, Ivanova S.M.2, Speransky L.I.2

1. Smolenskaya State Medical Academy
2. Institute of Rheumatology of RAMS
Section: Experimental/Clinical Study
PubMed Id: 16342671
Year: 2005  Volume: 51  Issue: 5  Pages: 536-541
The stade of lipid peroxidation and antioxidant defense was investigated in sera of 66 patients with rheumatoid arthritis (RA), 50 patients with systemic lupus erythematosus (SLE) and in 235 healthy donors using the method of chemiluminescence and EPR-spectroscopy. The results indicate involvement of free radical oxidation in pathogenesis of RA and SLE. Peroxide and antioxidant imbalance was more pronounced in RA than in SLE.
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Keywords: EPR-spectroscopy, chemiluminescence, rheumatoid arthritis, systemic lupus erythematosus, oxidative stress
Citation:

Podoprigorova, V. G., Bobilev, A. A., Ivanova, S. M., Speransky, L. I. (2005). Peculiarities of free radical antioxidant statute in patients with systemic lupus erythematosus and rheumatoid arthritis. Biomeditsinskaya Khimiya, 51(5), 536-541.
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