The influence of the 1-(2`-hydroxiethyl)-2-methyl-5-nitroimidazole on the state of erythrocyte membranes and their models

   
Kuznetsov P.E.1, Popyhova E.B.2 , Rogacheva S.M.2, Evlakov K.I.2

1. Saratov State University, Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences
2. Saratov State University
Section: Experimental/Clinical Study
PubMed Id: 16521827
Year: 2005  Volume: 51  Issue: 6  Pages: 649-655
Metronidazolum decreased diffusion mobility of membrane surface water. It is possible, that Wuk`s effect represents the molecular mechanism underlying this phenomenon. We suppose, that protective action of the derivatives of the nitroimidazole on cell lysis is related to changes of the diffusion mobility of the surface water
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Keywords: metronidasolum, biomembranes, surface water, erythrocytes
Citation:

Kuznetsov, P. E., Popyhova, E. B., Rogacheva, S. M., Evlakov, K. I. (2005). The influence of the 1-(2`-hydroxiethyl)-2-methyl-5-nitroimidazole on the state of erythrocyte membranes and their models. Biomeditsinskaya khimiya, 51(6), 649-655.
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