The effect of experimental burn trauma (20%) on myeloperoxidase (MPO) and antioxidant enzymes (catalase, glutathione peroxidase (GPO), glutathione-S-transferase (GST)) was studied in unburned skin, epidermis (20 mm from the burned area) and the wound tissue of rats. The most common features were the increase of MPO on the 1st day and a delayed increase of GPO and GST after the 4th day. The additional operations (necrectomy) and lipopolysaccharide administration induced marked inflammatory reaction in skin and epidermis (evaluated by the increase in MPO and GPO/GST activities).
Mikhal'chik E.V. et al. Antioxidant enzymes in skin experimental burn trauma // Biomeditsinskaya Khimiya. - 2006. - V. 52. -N 6. - P. 576-586.
Mikhal'chik E.V. et al., "Antioxidant enzymes in skin experimental burn trauma." Biomeditsinskaya Khimiya 52.6 (2006): 576-586.
Mikhal'chik, E. V., Titkova, S. M., Anurov, M. V., Pen'kov, L. Yu., Korkina, L. G. (2006). Antioxidant enzymes in skin experimental burn trauma. Biomeditsinskaya Khimiya, 52(6), 576-586.
Baskaran H., Yarmush M.L., Berthiamue F. (2000) J.Surg Res., 93, 88-96. Scholar google search
Porto da Rocha R., Lucio D.P., de Lima Souza T., Pereira S.T., Fernandes G.J.M. (2002) Aesth. Plast.Surg., 26, 197-202. Scholar google search
Oliveira G.V., Shimoda K., Enkhbaatar P., Jodoin J., Burke A.S., Chinkes D.L., Hawkins H.K., Herdndon D.N., Traber L., Traber D., Murakami K. (2004) Shock, 22, 278-282. Scholar google search
Goldstein R.K., Augustin A., Milz J ., Burg G., Lutz J. (1992) in Oxygen Transport to Tissue XIII (Goldstick et al ed.), Plenum Press, N.Y., pp.253-258. Scholar google search
Thiele J.J., Schroeter C., Hsieh S.N., Podda M., Packer L. (2001) in Oxidants and Antioxidants in Cutaneous Biology. Curr. Probl. Dermatol. (Thiele J., Elsner P. eds), Basel, Karger, vol.29, pp 26-42. Scholar google search
Steiling H., Munz B., Werner S., Brauchle M. (1999) Exp.Cell Res., 247, 484-494. Scholar google search
Hanselmann C., Mauch C., Werner S. (2001) Biochem. J., 353, 459-466. Scholar google search
Naziroglu M., Kokcam I., Yilmaz S. (2003) Skin Pharmacol. Appl. Skin Physiol., 16, 36-45. Scholar google search
Garner W.L., Rodriguez J.L., Miller C.G., Till G.O., Rees R.S., Smith D.J., Remick D.G. (1994) Surgery, 116, 42-48. Scholar google search
Troshev K., Kozarev I., Markov D. (1990) Acta Chir. Plast., 32, 152-163. Scholar google search
Lowry O.H., Rosebrough N.J., Farr A.L, Randall R.J. (1951) J. Biol. Chem., 193, 265-275. Scholar google search
Andrews P.C., Krinsky N.I. (1985) in CRC Handbook of Methods for Oxygen Radical Research (Greenwaid R., ed.), Boca Raton, Florida, pp. 297-302. Scholar google search
