The influence of silistrong on the activity of erythrocyte cytoplasmatic dehydrogenases and also purified glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was studied. Silistrong and its biologically active components (ethanol and silimarine) were found to activate GAPDH, lactate dehydrogenase (LDH), α-glycerophosphate dehydrogenase (GPDH) both in lysates of erythrocytes and in isolated GAPDH.The compounds studied are able to protect these enzymes and also to restore their activity of enzymes modified by hydrogen peroxide. Maximal activity is a characteristic of silistrong.
Gilmiyarova F.N., Radomskaya V.M., Myakisheva Yu.V., Baisheva G.M., Pervova Yu.V., Spiridonova N.V. (2006) The role of small molecules in regulation of activity of cytoplasmatic dehydrogenases. Biomeditsinskaya Khimiya, 52(6), 587-594.
Gilmiyarova F.N. et al. The role of small molecules in regulation of activity of cytoplasmatic dehydrogenases // Biomeditsinskaya Khimiya. - 2006. - V. 52. -N 6. - P. 587-594.
Gilmiyarova F.N. et al., "The role of small molecules in regulation of activity of cytoplasmatic dehydrogenases." Biomeditsinskaya Khimiya 52.6 (2006): 587-594.
Gilmiyarova, F. N., Radomskaya, V. M., Myakisheva, Yu. V., Baisheva, G. M., Pervova, Yu. V., Spiridonova, N. V. (2006). The role of small molecules in regulation of activity of cytoplasmatic dehydrogenases. Biomeditsinskaya Khimiya, 52(6), 587-594.
