Iron metabolism in biological systems (biochemical, pathophysiological and clinical perspectives)

   
Orlov Yu.P.1, Dolgich V.T.2

1. Municipal Clinic of Emergency Hospital №1
2. Omsk State Medical Academy
Section: Review
UDK: 616-008.9-092.6+546.72      PubMed Id: 17436682
Year: 2007  Volume: 53  Issue: 1  Pages: 25-38
Modern concepts concerning iron metabolisms in the body, its circulation, involvement into free radical processes and lipid peroxidation (LP) are reviewed. Spetial attention is paid to cytotoxic effects, Fe2+ influence on lipid peroxidation, its role in multiple organ failure development in critical states. Iron ion can be bound by desferal, which may be effectively used for intensive care of critical states.
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Reference:

Orlov Yu.P., Dolgich V.T. (2007) Biomeditsinskaya khimiya, 53(1), 25-38.
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