Biochemical and photometric studies of modification of collagen structure under UV radiation

   
Rebrova G.A.1 , Vasilevsky V.K.1, Rebrov L.B.1, Osipova L.A.1, Bykov V.A.1

1. Scientific Research and Eduction Centre of Biomedical Technology
Section: Experimental/Clinical Study
PubMed Id: 18035725
Year: 2007  Volume: 53  Issue: 4  Pages: 442-453
The influence of UV irradiation (270-380 nm) on the biochemical, fluorescence and colorimetric properties of collagen was studied. The long-term UV irradiation (120 h) was accompanied by the increase of structural stability of collagen to specific and nonspecific proteolytic enzymes, by formation of new additional fluorophore-containing molecules, by the increase in quantity of carbonyl groups in the collagen and by strong changing of the distribution pattern of alkaline hydrolysis products during gel-chromatography. The coordinates of colour of the collagen films are also changed. These changes of collagen suggest that UV irradiation induces photomodification and photooxidation processes in collagen.
Download PDF:
Keywords: collagen, UV radiation, photochemistry, photoaging
Citation:

Rebrova, G. A., Vasilevsky, V. K., Rebrov, L. B., Osipova, L. A., Bykov, V. A. (2007). Biochemical and photometric studies of modification of collagen structure under UV radiation. Biomeditsinskaya khimiya, 53(4), 442-453.
This paper is also available as the English translation: 10.1134/S1990750807040129
References  
 2022 (vol 68)
 2021 (vol 67)
 2020 (vol 66)
 2019 (vol 65)
 2018 (vol 64)
 2017 (vol 63)
 2016 (vol 62)
 2015 (vol 61)
 2014 (vol 60)
 2013 (vol 59)
 2012 (vol 58)
 2011 (vol 57)
 2010 (vol 56)
 2009 (vol 55)
 2008 (vol 54)
 2007 (vol 53)
 2006 (vol 52)
 2005 (vol 51)
 2004 (vol 50)
 2003 (vol 49)