Penetration of a virus into a host cell comprises the first step of the viral life cycle. Blockage of this process can stop or prevent the rise of the infection. In order to develop substances that show directed blocking activity, one should know which host cell and viral molecules are involved in the reciprocal recognition and interaction leading to the virus entry into the cell. This review is devoted to the problems of the identification of cell outer membrane molecules that participate in the hepatitis C virus binding and its transfer inside the cells. The putative role of these molecules as hepatitis C virus receptors and coreceptors in the beginning and development of the infection is discussed.
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Keywords: hepatitis C virus, receptors, envelope glycoproteins
Nikolaeva L.N., Olenina L.V., Kolesanova E.F. (1999) Russ. J. Immunol., 4, 91-112. Scholar google search
Шахгильдян И.В., Михайлов М.И., Онищенко Г.Г. (2003) Парентеральные вирусные гепатиты (эпидемиология, диагностика, профилактика), ГОУ ВУНМЦ МЗ РФ, М. Scholar google search
Kaito M., Watanabe S., Tsukiyama-Kohara K., Yamaguchi K., Kobayashi Y., Konishi M., Yokoi M., Ishida S., Suzuki S., Kohara M. (1994) J. Gen. Virol., 75, 1755-1760. Scholar google search
Prince A.M., Huima-Byron T., Parker T.S., Levine D.M. (1996) J. Viral Hepat., 3, 11-17. Scholar google search
Op De Beeck A., Cocquerel L., Dubuisson J. (2001) J. Gen. Virol., 82, 2589-2595. Scholar google search
Agnello V., Abel G., Elfahal M., Knight G., Zhang Q.X. (1999) Proc. Natl. Acad. Sci. USA, 96, 12766-12771. Scholar google search
Andre P., Komurian-Pradel F., Deforges S., Perret M., Berland J.L., Sodoyer M., Pol S., Brechot C., Paranhos-Baccala G., Lotteau V. (2002) J. Virol., 76, 6919-6928. Scholar google search
Nielsen S.U., Bassendine M.F., Burt A.D., Martin C., Pumeechockchai W., Toms G.L. (2006) J. Virol., 80, 2418-2428. Scholar google search
Masalova O.V., Atanadze S.N., Samokhvalov E.I., Petrakova N.V., Kalinina T.I., Smirnov V.D., Khudyakov Y.E., Fields H.A., Kushch A.A. (1998) J. Med. Virol., 55, 1-6. Scholar google search
Kolykhalov A.A., Agapov E.V., Blight K.J., Mihalik K., Feinstone S.M., Rice C.M. (1997) Science, 277, 570-574. CrossRef Scholar google search
Yanagi M., Purcell R.H., Emerson S.U., Bukh J. (1997) Proc. Natl. Acad. Sci. USA, 94, 8738-8743. Scholar google search
Kohara M., Kohara K., Kaito M., Inoue K., Amato Y., Ito T., Yasui K., Watanabe S. (2000) in: 7th International Meeting on Hepatitis C and Related Viruses, Australia, A 033. Scholar google search
Xie Z.C., Riezu-Boj J.I., Lasarte J.J., Guillen J., Su J.H., Civeira M.P., Prieto J. (1998) Virology, 244, 513-520. Scholar google search
Yi M., Villanueva R.A., Thomas D.L., Wakita T., Lemon S.M. (2006) Proc. Natl. Acad. Sci. USA, 103, 2310-2315. Scholar google search
Keck Z.Y., Xia J., Cai Z., Li T.K., Owsianka A.M., Patel A.H., Luo G., Foung S.K. (2007) J. Virol., 81, 1043-1047. Scholar google search
Hsu M., Zhang J., Flint M., Logvinoff C., Cheng-Mayer C., Rice C.M., McKeating J.A. (2003) Proc. Natl. Acad. Sci. USA, 100, 7271-7276. Scholar google search
Meertens L., Bertaux C., Dragic T. (2006) J. Virol., 80, 11571-11578. Scholar google search
Deleersnyder V., Pillez A., Wychowski C., Blight K., Xu J.,Hahn Y.S., Rice C.M., Dubuisson J. (1997) J. Virol., 71, 697-704. Scholar google search
Pileri P., Uematsu Y., Campagnoli S., Galli G., Falugi F., Petracca R., Weiner A.J., Houghton M., Rosa D., Grandi G., Abrignani S. (1998) Science, 282, 938-941. CrossRef Scholar google search
Allander T., Forns X, Emerson S.U., Purcell R.H., Bukh J. (2000) Virology, 277, 358-367 . Scholar google search
Baumert T.F., Ito S., Wong D. Liang T.J. (1998) J. Virol., 72, 3827-3836. Scholar google search
Triyatni M., Saunier B., Maruvada P., Davis A.R., Ulianich L., Heller T., Patel A., Kohn L.D., Liang T.J. (2002) J. Virol., 76, 9335-9344. Scholar google search
Bartosch B., Dubuisson J., Cosse, F.-L. (2003) J. Exp. Med., 197, 633-642. Scholar google search
Bartosch B., Vitelli A., Granier C., Goujon C., Dubuisson J., Pascale S., Scarselli E., Cortese R., Nicosia A., Cosset F.L. (2003) J. Biol. Chem., 278, 41624-41630. Scholar google search
Hijikata M., Shimizu Y.K., Kato H., Iwamoto A., Shih J.W., Alter H.J., Purcell R.H., Yoshikura H. (1993) J. Virol., 67, 1953-1958. Scholar google search
Germi R., Crance J.M., Garin D., Guimet J., Lortat-Jacob H., Ruigrok R.W., Zarski J.P., Drouet E. (2002) J. Med. Virol., 68, 206-215. Scholar google search
Molina S., Castet V., Fournier-Wirth C., Pichard-Garcia L., Avner R., Harats D., Roitelman J., Barbaras R., Graber P., Ghersa P., Smolarsky M., Funaro A., Malavasi F., Larrey D., Coste J., Fabre J.M., Sa-Cunha A., Maurel P. (2007) J. Hepatol., 46, 411-419. Scholar google search
Enjoji M., Nakamuta M., Kinukawa N., Sugimoto R., Noguchi K., Tsuruta S., Iwao M., Kotoh K., Iwamoto H., Nawata H. (2000) Med. Sci. Monit., 6, 841-844. Scholar google search
Levy S., Todd S.C., Maecker H.T. (1998) Annu. Rev. Immunol., 16, 89-109. Scholar google search
Ройт А., Бростофф Дж., Мейл Д. (2000) Иммунология. (Пер. с англ.), Мир, М. Scholar google search
Petracca R., Faludgi F., Galli G., Norais N., Rosa D., Campagnoli S., Burgio V., Stasio E., Giardina B., Houghton M., Abrignani S., Grandi G. (2000) J. Virol., 74, 4824-4830. Scholar google search
Robey F.A., Harris-Kelson T., Robert-Guroff M., Batinic D., Ivanov B., Lewis M.S., Roller P.P. (1996) J. Biol. Chem., 271, 17990-17995. Scholar google search
Flint M., von Hahn T., Zhang J., Farquhar M., Jones C.T., Balfe P., Rice C.M., McKeating J.A. (2006) J. Virol., 80, 11331-11342. Scholar google search
Zhang J., Randall G., Higginbottom A., Monk P., Rice C.M., McKeating J.A. (2004) J. Virol., 78, 1448-1455. Scholar google search
Henry S.D., van der Wegen P., Metselaar H.J., Tilanus H.W., Scholte B.J., van der Laan L.J. (2006) Mol. Ther., 14, 485-493. Scholar google search
Koutsoudakis G., Herrmann E., Kallis S., Bartenschlager R., Pietschmann T. (2007) J. Virol., 81, 588-598. Scholar google search
Cormier E.G., Tsamis F., Kajumo F., Durso R.J., Gardner J.P., Dragic T. (2004) Proc. Natl. Acad. Sci. USA, 101, 7270-7274. Scholar google search
Crotta S., Stilla A., Wack A., D`Andrea A., Nuti S., D`Oro U., Mosca M., Filliponi F., Brunetto R.M., Bonino F., Abrignani S., Valiante N.M. (2002) J. Exp. Med., 195, 35-41. Scholar google search
Nattermann J., Zimmermann H., Iwan A., von Lilienfeld-Toal M., Leifeld L., Nischalke H.D., Langhans B., Sauerbruch T., Spengler U. (2006) Hepatology, 44, 945-954. Scholar google search
Soldaini E., Wack A., D`Oro U., Nuti S., Ulivieri C., Baldari C.T., Abrignani S. (2003) Eur. J. Immunol., 33, 455-464. Scholar google search
Machida K., Cheng K.T., Pavio N., Sung V.M., Lai M.M. (2005) J. Virol., 79, 8079-8089. Scholar google search
Zuckerman E., Kessel A., Slobodin G., Sabo E., Yeshurun D., Toubi E. (2003) J. Virol., 77, 10432-10436. Scholar google search
Curry M.P., Golden-Mason L., Doherty D.G., Deignan T., Norris S., Duffy M., Nolan N., Hall W., Hegarty J.E., O`Farrelly C. (2003) J. Hepatol., 38, 642-650. Scholar google search
Ni J., Hembrador E., Di Bisceglie A.M., Jacobson I.M., Talal A.H., Butera D., Rice C.M., Chambers T.J., Dustin L.B. (2003) J. Immunol., 170, 3429-3439. Scholar google search
Rosa D., Saletti G., De Gregorio E., Zorat F., Comar C., D`Oro U., Nuti S., Houghton M., Barnaba V., Pozzato G., Abrignani S. (2005) Proc. Natl. Acad. Sci. USA, 102, 18544-18549. Scholar google search
Scarselli E., Ansuini H., Cerino R., Roccasecca R.M., Acali S., Filocamo G., Traboni C., Nicosia A., Cortese R., Vitelli A. (2002) EMBO J., 21, 5017-5025. Scholar google search
Voisset C., Callens N., Blanchard E., Op De Beeck A., Dubuisson J., Vu-Dac N. (2005) J. Biol. Chem., 280, 7793-7799. Scholar google search
Voisset C., Op de Beeck A., Horellou P., Dreux M., Gustot T., Duverlie G., Cosset F.L., Vu-Dac N., Dubuisson J. (2006) J. Gen. Virol., 87, 2577-2581. Scholar google search
Saunier B., Triyatni M., Ulianich L., Maruvada P., Yen P., Kohn L.D. (2003) J. Virol., 77, 546-559. Scholar google search
Dotzauer A., Gebhardt U., Bieback K., Gottke U., Kracke A., Mages J., Lemon S.M., Vallbracht A. (2000) J .Virol., 74, 10950-10957. Scholar google search
Meier M., Bider M.D., Malashkevich V.N., Spiess M., Burkhard P. (2000) J. Mol. Biol., 300, 857-865. Scholar google search
Gardner J.P., Durso R.J., Arrigale R.R., Donovan G.P., Maddon P.J., Dragic T., Olson W.C. (2003) Proc. Natl. Acad. Sci. USA, 100, 4498-4503. Scholar google search
Lozach P.Y., Lortat-Jacob H., de Lacroix D.L., Staropoli I., Foung S., Amara A., Houles C., Fieschi F., Schwartz O., Virelizier J.L., Arenzana- Seisdedos F., Altmeyer R. (2003) J. Biol. Chem., 278, 20358-20366. Scholar google search
Pohlmann S., Zhang J., Baribaud F., Chen Z., Leslie G.J., Lin G., Granelli-Piperno A., Doms R.W., Rice C.M., McKeating J.A. (2003) J. Virol., 77, 4070-4080. Scholar google search
Geijtenbeek T.B., Engering A., Van Kooyk Y.J. (2002) J. Leukoc. Biol., 71, 921-931. Scholar google search
Curtis B.M., Scharnowske S., Watson A.J. (1992) Proc. Natl. Acad. Sci. USA, 89, 8356-8360. Scholar google search
Soilleux E.J., Morris L.S., Lee B., Pohlmann S., Trowsdale J., Doms R.W., Coleman N. (2001) J. Pathol., 195, 586-592. Scholar google search
Soilleux E.J., Morris L.S., Leslie G., Chehimi J., Luo Q., Levroney E., Trowsdale J., Montaner L.J., Doms R.W., Weissman D., Coleman N., Lee B. (2002) J. Leukoc. Biol., 71, 445-457. Scholar google search
Mitchell D.A., Fadden A.J., Drickamer K. (2001) J. Biol. Chem., 276, 28939-28945. Scholar google search
Pohlmann S., Soilleux E.J., Baribaud F., Leslie G.J., Morris L.S., Trowsdale J., Lee B., Coleman N., Doms R.W. (2001) Proc. Natl. Acad. Sci. USA, 98, 2670-2675. Scholar google search
Geijtenbeek T.B., Kwon D.S., Torensma R., van Vliet S.J., van Duijnhoven G.C., Middel J., Cornelissen I.L., Nottet H.S., KewalRamani V.N., Littman D.R., Figdor C.G., Van Kooyk Y. (2000) Cell, 100, 587-597. Scholar google search
Alvarez C.P., Lasala F., Carrillo J., Muniz O., Corbi A.L., Delgado R. (2002) J. Virol., 76, 6841-6844. Scholar google search
Tassaneetrithep B., Burgess T.H., Granelli-Piperno A., Trumpfheller C., Finke J., Sun W., Eller M.A., Pattanapanyasat K., Sarasombath S., Birx D.L., Steinman R.M., Schlesinger S., Marovich M.A. (2003) J. Exp. Med., 197, 823-829. Scholar google search
Halary F., Amara A., Lortat-Jacob H., Messerle M., Delaunay T., Houles C., Fieschi F., Arenzana-Seisdedos F., Moreau J.F., Dechanet-Merville J. (2002) Immunity, 17, 653-664. Scholar google search
Tailleux L., Schwartz O., Herrmann J.L., Pivert E., Jackson M., Amara A., Legres L., Dreher D., Nicod L.P., Gluckman J.C., Lagrange P.H., Gicquel B., Neyrolles O. (2003) J. Exp. Med., 197, 121-127. Scholar google search
Maeda N., Nigou J., Herrmann J.L., Jackson M., Amara A., Lagrange P.H., Puzo G., Gicquel B., Neyrolles O. (2003) J. Biol. Chem., 278, 5513-5516. Scholar google search
Lin G., Simmons G., Pohlmann S., Baribaud F., Ni H., Leslie G.J., Haggarty B.S., Bates P., Weissman D., Hoxie J.A., Doms R.W. (2003) J. Virol., 77, 1337-1346. Scholar google search
Engering A., Geijtenbeek T.B., van Vliet S.J., Wijers M., van Liempt E., Demaurex N., Lanzavecchia A., Fransen J., Figdor C.G., Piguet V., van Kooyk Y. (2002) J. Immunol., 168, 2118-2126. Scholar google search
Martire G., Viola A., Iodice L., Lotti L.V., Gradini R., Bonatti S. (2001) Virology, 280, 176-182. Scholar google search
Ludwig I.S., Lekkerkerker A.N., Depla E., Bosman F., Musters R.J., Depraetere S., van Kooyk Y., Geijtenbeek T.B. (2004) J. Virol., 78, 8322-8332. Scholar google search
Turnbull J., Powell A., Guimond S. (2001) Trends Cell Biol., 11, 75-82. Scholar google search
Lyon M., Deakin J.A., Gallagher J.T. (1994) J. Biol. Chem., 269, 11208-11215. Scholar google search
Akula S.M., Pramod N.P., Wang F.Z., Chandran B. (2001) Virology, 284, 235-249. Scholar google search
Moulard M., Lortat-Jacob H., Mondor I., Roca G., Wyatt R., Sodroski J., Zhao L., Olson W., Kwong P.D., Sattentau Q.J. (2000) J. Virol., 74, 1948-1960. Scholar google search