The effect of ozonated saline on proteolytic enzymes: trypsin, chymotrypsin, elastase, kallikrein, leucine aminopeptidase, inhibitors of proteolysis and lipid peroxidation has been investigated. Injection of ozonated saline led to significal response of proteolytic system. Ozonated saline with low ozone doses produced a positive effect on proteolytic system. High doses of ozone produced significal reinforcement of proteolytic system and the decrease of α1-antitrypsin and α2-macroglobulin activity in blood plasma. Therefore, analyses of proteolytic activity can be used as indicator of effectiveness and safety of ozonetherapy and others treatment programms.
Yefremenko J.R. (2008) The proteolytic enzymes - highly sensitive criterium of effectiveness and safety of treatment. Biomeditsinskaya Khimiya, 54(2), 179-183.
et al. The proteolytic enzymes - highly sensitive criterium of effectiveness and safety of treatment // Biomeditsinskaya Khimiya. - 2008. - V. 54. -N 2. - P. 179-183.
et al., "The proteolytic enzymes - highly sensitive criterium of effectiveness and safety of treatment." Biomeditsinskaya Khimiya 54.2 (2008): 179-183.
Yefremenko, J. R. (2008). The proteolytic enzymes - highly sensitive criterium of effectiveness and safety of treatment. Biomeditsinskaya Khimiya, 54(2), 179-183.
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